Skip to main content
Average ER Wait Time
Checking ER Wait Time
The feed could not be reached
Northside Hospital
Provider facility background
Michael P Defrain, MD

Michael P Defrain, MD

General Surgery
Michael Patrick DeFrain, M.D. was born and raised in East Lansing, Michigan. After completing his undergraduate degree at the University of Michigan, he was awarded his medical degree from Wayne State University. His general surgery residency was also completed in Michigan at Michigan State University. Dr. DeFrain then moved to Texas to attend the Texas Heart Institute for his cardiothoracic surgery residency. While there, Dr. DeFrain had the privilege of training and operating with the world-renowned heart surgeon, Dr. Denton Cooley. He has extensive training in minimally invasive valve surgery and mitral valve repair. His professional focus is centered on efforts to develop new techniques that utilize the least invasive methods to accomplish coronary bypass, valve repair, and other heart operations. Dr. DeFrain is a diplomate of the American Board of Surgery and the American Board of Thoracic Surgery. His professional memberships include: The Denton A. Cooley Cardiovascular Surgical Society, The Society of Thoracic Surgeons, The Southern Thoracic Surgical Association and The American College of Surgeons. Dr. DeFrain is deeply committed to his patients and their families. In his free time, Dr. DeFrain enjoys kite surfing and spending weekends at the beach in Florida, or the lakes of Michigan with his wife Stephanie and their three children.
Care Philosophy

Dr. DeFrain believes that the best surgical results are achieved when operative techniques are simplified with the least possible physical impact on the patient.

I would like to schedule ...

Auto Accident Insurance

Workmans Group



Atrial Fibrillation - AFib

Cardiovascular Aorta

Cardiovascular Bypass

Cardiovascular Minimally Invasive Valve Repair and Replacement

Cardiovascular Mitral Valve Prolapse Syndrome

Cardiovascular Transmyocardial Revascularization

Coronary Artery Bypass Graft Surgery (CABG)

Coronary Artery Disease

Healthcare Exchange

Heart Attack and Chest Pain (Angina)

Heart Surgery

Laser Procedure and Surgery



Minimally Invasive Cardiac Surgery

Minimally Invasive Heart Surgery

Minimally Invasive Thoracic Surgery - MITS


Peripheral Artery Disease

Peripheral Vascular Disease




TAVR (Transcatheter Aortic Valve Replacement)

Thoracic or Cardiothoracic Surgery

Transcatheter Aortic Valve Replacement (TAVR)

Valve Disease (including aortic stenosis and mitral valve disease)

Valve Repair and Replacement


Valvular Heart Disease

Video-Assisted Thoracic Surgery (VATS)

  • General Surgery - Primary
  • Cardio-Thoracic Surgery - Board Certified
  • Internship: Michigan State University - 2000
  • Residency: Michigan State University - 2005
  • Fellowship: Texas Heart Institute - 2008
  • Graduate Degree: Doctor Of Medicine - Wayne State University School of Medicine - 1998
  • English
  • Largo Medical Center - Indian Rocks
  • Largo Medical Center
  • Northside Hospital